Research Associate I/II, Development at Zymergen
Emeryville, CA, US
Zymergen is hiring a distinctive Research Associate to develop methods for high-throughput microbial strain engineering. The Research Associate will join a Development team that works in collaboration with partner companies to advance the tools and techniques applied to existing microbes used in large scale industrial fermentation. At Zymergen, the Research Associate will work together with other scientists, automation engineers, and software engineers to develop protocols for high-throughput microbial strain engineering, plate models for microbe growth and production, and then enable their use in high throughput workflows.

Immediate responsibilities include:

Building DNA assemblies using cutting edge molecular biology methods
Using software tools for DNA analysis and design
Transforming a variety of host microbes (bacteria, yeast, filamentous fungi)
Culturing a variety of host microbes in 96 well format
Applying a broad range of analytical methods including Pcr, DNA and protein electrophoresis, western blotting, spectrophotometry, and other plate based assays to qc and test strains
Using a broad range of analytical equipment for high-throughput sample analysis
Preparing materials including media and buffers, managing experiment schedules, processing materials, and collecting, storing and analyzing data
Using automation tools to increase experimental throughput
Communicating experimental results to the project team
The Development team is integral to the development of protocols that enable construction and screening of thousands of microbes per week. Members of the Development team need to be well-versed in molecular and microbiology, creative, organized, energetic, collaborative, and fully engaged in the execution of experiments. We need team members that are passionate about microbial engineering and excited to develop new methods and protocols.

QUALIFICATIONS/EXPERIENCE

We favor candidates with substantial experience designing and executing experiments in lab: MS with 2+ years of working experience, or a BS with 4+ years working experience. We are interested in candidates with technical training in biology, molecular biology, biochemistry, chemistry or engineering. Lastly, we look for candidates that have displayed excellence and high achievement in previous technical and non-technical work.

We prefer RAs with experience in some or all of the following areas.

Protocols and Equipment:

Familiarity with techniques in molecular biology, including pcr, dna assembly, dna sequencing sample prep, microbe transformation (bacteria, yeast, filamentous fungi); with cell physiology in microtiter plate models and in bench-scale fermentation; and with assay such as hplc, gc, plate-based enzymatic assays, or other optical measurements
Experience using lab automation (Beckman, Tecan, etc.) to enable complicated or high-throughput protocols
Proficiency in the use of analytical equipment such as plate readers, automated dna electrophoresis systems, or flow cytometry
Operations and Data Analysis:

Experience writing, optimizing, and following complicated SOPs
Capability to manage multiple ongoing multiday workflows, including preparing reagents and materials, and managing implementation
Familiarity with concepts in statistics, tools to analyze data such as excel, jmp, or Spotfire
Previous experience in the field of synthetic biology is a plus.

Our facilities are located in the San Francisco Bay Area.