Scientist/ Scientist II at Synthetic Genomics
La Jolla, CA, US
At Synthetic Genomics, Inc., we are dedicated to developing and commercializing genomic-driven solutions to address global challenges. We are currently seeking a Scientist I/II to join our fast-growing, dynamic and collaborative team in La Jolla, CA.
The Scientist I/II will join the vaccines R&D team within the Viral Systems Unit, which focuses on the development of novel RNA-based vaccines in the fields of emerging diseases and cancer. The successful candidate will play a key role in development and implementation of immune functional assays, in vivo assessment of formulations, and in vivo characterization of immunogenicity and efficacy of vaccine lead candidates. The role will also be involved in mechanism of action studies as well as in vivo evaluation and optimization of vaccine platforms. This position requires strong cellular immunology expertise with demonstrated research productivity in the fields of immunology and/or vaccinology.
• Up-to-date knowledge of cellular immunology and vaccinology is required
• Foundation of knowledge in immuno-oncology and molecular biology is highly preferred
• Expertise in the design, execution, and analysis of in vivo evaluations of immunogenicity and efficacy is required
• Demonstrated ability to setup and perform functional immune assays
• Time management, prioritization, and planning skills with the ability to execute multiple projects and provide technical leadership to research associates in cross-disciplinary team environments
• Ability to represent SGI at scientific presentations and meetings
• PhD in Immunology, Microbiology, Virology or related field
• Minimum of two-years post-doctoral level training
• Experience working with CROs and managing external projects across different geographic locations is highly preferred
• Direct, hands-on experience with, and extensive knowledge of, cellular immunology, cell-based immune functional assays, flow cytometric analysis and isolation of transformed and primary cells, assays for correlates of protection, molecular (DNA/RNA/protein) assays and relevant statistical analysis.
• Track record of successful research involving immunology and/or vaccine development required
• Excellent communication and interpersonal skills to facilitate internal and external scientific interactions
• Organized, highly motivated, innovative professional with critical thinking and problem-solving skills to independently design, execute, troubleshoot and interpret experiments
• Strong knowledge of vaccine technologies highly preferred